I had a classic case of what people call "seeker's disease." That was part of my journey, but now, meaning is like a secret that's revealing itself moment by moment, day by day.
If you want to avoid Alzheimer's disease, sleep 8 hours a night.
We've just done a five-day retreat at the Chopra centre and people who went to the meditation retreat saw their anti-ageing enzyme increase by 40 per cent. We looked at their 23,000 genes and the self-healing genes were up regulated and all the genes related to heart disease, cancer and inflammatory diseases, diabetes, they all went down within five days.
You could almost say that throughout human history there are people who can either foresee consequences or who are capable of looking for information and predicting the consequences will happen, but the vast majority of people won't respond to climate change until their city is underwater, food supply is disrupted or everyone around them is dying of zoonotic disease. It's almost like someone dealing with an addiction, like you hope that the person can overcome the addiction before the addiction kills them.
There are so many symptoms of this disease it's hard to know where to start to catalogue them, but just look at the effects on hydrology - on the way water moves around the planet.
Technology didn't just go, clunk. It was this early disease, starting with a plow, I guess, or something like that, the first tool that made it so you could do more things. The first domesticated animal, or the first wheel.
Just as an informal, nonscientific observation, most people's personalities don't seem to change very much during their lives. There are exceptions in the case of people who go through hugely traumatic events or suffer from brain injury or disease. Some would argue that religious conversions can have deep personality-altering effects. But these are all exceptions to the rule.
The Andromeda strain is a killer disease that they've got to prevent from spreading to being 100 percent contagious. It's another one where we're racing to save humanity.
Suppose that I see a hungry child in the street, and I am able to offer the child some food. Am I morally culpable if I refuse to do so? Am I morally culpable if I choose not to do what I easily can about the fact that 1000 children die every hour from easily preventable disease, according to UNICEF? Or the fact that the government of my own "free and open society" is engaged in monstrous crimes that can easily be mitigated or terminated? Is it even possible to debate these questions?
AIDS we're - most of these diseases - we are down from the peak. We're down about 40 per cent from the peak and if we got the right vaccines, which are at the early stage of discovering, then the numbers would come down very dramatically. So that's why we talk about it as an emergency.
We have two other countries, Pakistan and Afghanistan - again it's the instability that is a problem there. So over the next several years, we expect to drive the number of [polio] cases back down to zero because that is likely to be the second disease after smallpox that we completely eradicate.
For all these infectious diseases, the goal is to eventually get rid of them. And to do that we need to invent new tools, but nobody was doing that because there was no money to buy on behalf of the poorest, even the existing tools.
I'll get to see many disease eradications. and we're seeing a lot of progress.
Maybe I've been a small part of the democratisation of celebrity, because I've been fascinated by it, and when it started to happen to me to the very limited extent that it happens to writers in North America, I was exposed to people who had the disease of celebrity. People who had raging, raging, life-threatening celebrity, people who would be in danger if they were left alone on the street without their minders. It's a great anthropological privilege to be there.
What I regretted in La Nausee was not to have put myself completely into the thing. I remained outside my hero's disease, protected by my neurosis which, through writing, gave me happiness.
The medical profession [in Egypt] is also very commercial. Health is not given to the poor. You know, if you have money, you have medical care; if you do not, then you are in trouble. I was not ready at all to build my economic security on the diseases of people, on suffering, especially of women and children. So, in a way, I rebelled against it.
The scientific understanding of some of these [childhood] diseases is advancing quite rapidly. There's some things like premature birth or nutrition, first day deaths that we need a lot more insights so that we can build the tools to solve those problems.
Even for the diseases we don't focus on, cancer, heart disease, you're going to be way better off being sick 10 years from now than any time in the past.
In the philanthropy game, you're going for different outcomes: saving childhood lives, having kids grow up - because they don't have malnutrition or disease - that they achieve their full potential. We take for Warren [Buffett] things that, because he's very intelligent about the world but doesn't get to go out in Africa and see what we see, we've taken and say to him where we stand and it's basically a very positive report that his gift has made a phenomenal difference.
[Warren Buffett ] met with all sorts of different groups about a lot of different things, but yes, he took the time, he listened and he wanted to understand about some of the different diseases and the strength of the American role in doing all these things.
Vaccines are a miracle; they're fantastic. Anything that makes people hesitate to give their children these vaccines according to the recommended schedule creates risk. Risk for the children who don't get vaccinated and risk for children, some of whom don't have an immune system, so they're benefiting from the fact that the community protection means the disease doesn't get to them.
If somebody is working on a new medicine, computer science helps us model those things. We have a whole group here in Seattle called the Institute for Disease Modelling that is a mix of computer science and math-type people, and the progress we're making in polio or plans for malaria or really driven by their deep insights.
If you go out and have unprotected sex with lots of people, that behavior puts you at risk. Similarly, violent behavior can spread. One violent act can elicit a response. It can spread to people in a peer group so that they feel that they have to respond. It can pass generation to generation almost like a genetic disease.
Violence can behave like a disease. That insight gives a different frame of reference that is designed to take the judgment out of it, to take the good-versus-bad-people view out of it.
We have the opportunity now to look at the two billion people in the world who suffer from the most abject poverty, hunger, disease, and devastation. Add to that another two billion people who are just plain poor. If you look into the world of those caught in economic oppression, illiteracy, disease, and sexism, then you'll understand more clearly what we have to do.
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