The lower animals, on the other hand, must have their bodily structure modified in order to survive under greatly changed conditions. They must be rendered stronger, or acquire more effective teeth or claws, in order to defend themselves from new enemies; or they must be reduced in size so as to escape detection and danger. When they migrate into a colder climate they must become clothed with thicker fur, or have their constitutions altered. If they fail to be thus modified, they will cease to exist.